Gene DNASE1L3 Details
It offers a comprehensive overview of all clinically relevant variants linked to a specified gene. It provides detailed metrics for each variant, including chromosomal position, HGVS c. and p. notation, allele frequencies, carrier rates, and estimated metrics for at-risk couples. By combining gene-level statistics with specific variant-level data, this page enables an in-depth analysis of how particular genes contribute to disease, thus supporting both clinical interpretation and research efforts.
Gene: DNASE1L3
Disorder: Systemic lupus erythematosus 16
Allele Frequency: 0.00167504
Carrier Rate: 0.00334447
Max At-Risk Couples rate: 0.0000112
The table below lists all clinically relevant variants identified in the DNASE1L3 gene based on the Emirati cohort dataset.
| id |
Chromosome Position |
Gene Name |
HGVS c. (Clinically Relevant) |
HGVS p. (Clinically Relevant) |
Allele Count |
Allele Frequency |
| 266 |
58183609 |
DNASE1L3 |
NM_004944.4:c.643delT |
NP_004935.1:p.Trp215Glyfs*2 |
2 |
0.000838% |
| 267 |
58191227 |
DNASE1L3 |
NM_004944.4:c.290_291delCA |
NP_004935.1:p.Thr97Ilefs*2 |
2 |
0.000838% |
