Gene TTC37 Details
It offers a comprehensive overview of all clinically relevant variants linked to a specified gene. It provides detailed metrics for each variant, including chromosomal position, HGVS c. and p. notation, allele frequencies, carrier rates, and estimated metrics for at-risk couples. By combining gene-level statistics with specific variant-level data, this page enables an in-depth analysis of how particular genes contribute to disease, thus supporting both clinical interpretation and research efforts.
Gene: TTC37
Disorder: Fatigue, failure to thrive & diarrhoea
Allele Frequency: 0.00293132
Carrier Rate: 0.00584546
Max At-Risk Couples rate: 0.0000342
The table below lists all clinically relevant variants identified in the TTC37 gene based on the Emirati cohort dataset.
| id |
Chromosome Position |
Gene Name |
HGVS c. (Clinically Relevant) |
HGVS p. (Clinically Relevant) |
Allele Count |
Allele Frequency |
| 280 |
94813999 |
TTC37 |
NM_014639.4:c.4360delT |
NP_055454.1:p.Cys1454Valfs*22 |
2 |
0.000838% |
| 281 |
94856475 |
TTC37 |
NM_014639.4:c.2059delT |
NP_055454.1:p.Tyr687Ilefs*7 |
2 |
0.000838% |
| 282 |
94864753 |
TTC37 |
NM_014639.4:c.946delC |
NP_055454.1:p.Gln316Lysfs*18 |
2 |
0.000838% |
| 714 |
94877029 |
TTC37 |
NM_014639.4:c.382delC |
NP_055454.1:p.Gln128Lysfs*6 |
1 |
0.000419% |
